Fire officers were called to a house in The Drive, Kingsley, Northampton, after a fire broke out in the early hours of this morning (Tuesday 16 October).
The upper floor and roof were badly damaged by fire, causing the roof to collapse.
A 96-year-old woman and a 62-year-old man were rescued by crews, before being taken to Northampton General Hospital.
Northamptonshire Fire and Rescue Service were called just after 1am. The cause of the fire is currently being investigated.